Sunday, 3 July 2016

CT Angiography ...Understanding the Basics


The most common CT procedures that put everyone on edge are unarguably CT Angiography procedures. But then, Angiographies as technical as they may seem are really not a big deal. I am not going to talk about specific steps to angiography procedures. But however, I am going to give insights into some of the most basic things that every radiographer has to know before attempting to do an angiography successfully.
Angiography also called Arteriography (some texts can use angiogram or arteriogram; they all mean the same thing) is typically a study of the arteries. Ordinarily, the arteries are radiolucent and this necessitates that use of contrast media in angiography. Some of the most common angiographies requested include: cerebral angiography (circle of Willis), Carotid angiography, pulmonary angiography, renal angiography, abdominal aortic angiography, peripheral angiography or extremity angiography. Coronal (cardiac) angiography is obviously the most complicated and technical angiography and the request are usually not common.
Please bear in mind that the context here is CT angiographies which are studies of the arteries carried out using contrast enhanced computed tomography scans. Conventional Angiographies are mostly obsolete these days and you may never come across such a request in the department again.

Basics to understanding CT Angiography
For you to successfully attempt a CT angiography, you have to have fundamental knowledge of the following
1.       What kind of CT scanner do you have and how does it perform angiography?
 I have had discussions with Radiographers who tell me that their scanners cannot perform Angiographies. Well the truth is that all multi-slice detector scanners can perform Angiography scans but how well is what is to be argued. Once the machine is able to acquire thin slice volume images, it has the capacity of performing an angiography. But the issue of scan time is the reason why 16 slice CT scanners have been placed as the benchmark for CT angiography. The fundamental of a good angiography study is the ability for the scanner to match very thin slice image acquisition with very short scan time. Ideally, thin slices of 0.625mm -1.25mm are adequate for a good angiography study and will ensure adequate volume images obtained within a single breathe hold and at the time of arterial circulation with no venous circulation contamination. More details will be discussed subsequently but the key point here is that any scanner that allows 0.625-1.25mm slice thickness and a scan time of 5-25secs can perform a good angiography study.
Usually most scanners have already pre-set angiography protocols that has appropriate scan time, pitch, gantry rotation, slice thickness, exposure factors etc. Angiographies are always *compulsorily done with automatic injectors. You must also be familiar with how to operate the auto-injector and most important how to synchronize it with the scanning. (I will discuss that later).
2.       What kind of Angiography is being requested?
Like I pointed out earlier, there are different types of CT angiographies depending on the part of the body under review. So it is important that you have a good knowledge of the anatomy of arterial circulation. When you have a request for cerebral CT angiography, you are investigating arteries that make up the circle of willis and same goes for other angiography studies.
3.       Why was the angiography study requested? What is the doctor looking for?
You have an idea of what the clinical condition of the patient is and why the doctors are requesting for the angiography. If you don’t, you will not be properly guided in the procedure. You must ensure that the referring doctor(s) attached a clinical note detailing the conditions of the patient and the pathology under review. No clinical note…no CT angiography. 
The reasons for doing an angiography study can be generally grouped as follows:
·         To find an aneurysm (a blood vessel that has become enlarged and may be in danger of rupturing)
·         To find blood vessels that have become narrowed by atherosclerosis (fatty material that forms plaques in the walls of arteries)
·         To find abnormal blood vessel formations inside your brain
·         To identify blood vessels damaged by injury
·         To find blood clots that may have formed in your leg veins and traveled into your lungs.
·         To evaluate a tumor that is fed by blood vessels
 

4.       What are the preparations given to patients before the scan procedure?
In as much as CT angiography is presumed safe for the patient, you must carefully prepare the patient before the scan. The major concern is usually with the iodine contrast given to the patient. A small percentage of patients react to iodine contrast and as such all patients must be given the following instructions:
                                 i.            Do not eat atleast 4-5 hours before the scan. The reason for this is very simple. Patients can react to the iodine contrasts in form of vomiting (among others). A patient who has eaten within 4-5 hours have the tendency of vomiting food in the stomach and is likely to aspirate the food particles into the airways. That will cause serious injury and in extreme cases can lead to death.
                               ii.            Do a kidney function test for patients suspected of impaired kidney functions. Usually a creatinine test is done and a normal result is within the range of 0.7 to 1.3 mg/dL for men and 0.6 to 1.1 mg/dL for women. Some departments make it a routine to do a creatinine for all angiography patients; their reasons being precautionary.
                              iii.            For diabetic patients, metformin drug intake should be withheld for 48hours after contrast administration. The reason is that, metformin is excreted by the kidney and its accumulation is very toxic. The kidney also has to deal with excreting the iodine contrast agent and so it’s better to let the kidney excrete all the iodine contrast and we are sure that there is no kidney failure before metformin is restarted. If you were told before to withhold metformin intake 48 hours before and after contrast administration, please disregard that information.
                             iv.            Patients are allowed to take clear fluid and drugs not requiring food.
                               v.            It is important to take patients vitals before and after the procedure. Iodine contrast reactions can include rise in temperature, increased heart rate etc. Taking vitals will ensure adequate patient monitoring.
5.       Can you perform post processing/ reconstructions?
Scanning a patient is important; but image reformation is also as important because that where the images that make all the differences are displayed. You must learn how to do 3D volume rendering. This is usually best done in a work station; and trust me, that is where the real work is done. Your expertise with work stations makes a lot of difference. Spend time and learn it very well. Unfortunately, work station operations cannot just be discussed on prints. They are real time practical and get better with efforts in practice and learning.


this is what a post-processed 3D volume rendered cerebral CT angiography image looks like


 

MIP images for renal CT angiogram
                                                          
3D volume rendered images for renal CT angiogram

WE WILL REVIEW PRACTICAL APPROACHES TO CT ANGIOGRAPHY STUDIES IN SUBSEQUENT DISCUSSIONS.